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#118 Beat Ageing with Dr Andrew Steele


Details

Can we beat ageing?  This is the topic of today’s discussion and whilst you might think this is yet another dive into our narcissistic tendency to want to live forever and reduce the appearance of wrinkles, the field of ageing and how to reverse it ( known as biogerontology) is actually about beating cancer, dementia, strokes and all the things that become exponentially more likely after the age of 50. 

Dr Andrew Steele PhD is a scientist, writer and campaigner based in London, and author of Ageless: The new science of getting older without getting old. After a PhD in physics from the University of Oxford, he decided that ageing was the single most important scientific challenge of our time, and switched fields to computational biology.

His latest book, dives into the history of ageing research, what we understand about ageing today as well as why in as little as the next few years, I as a doctor, might be able to prescribe a suite of anti-ageing drugs.

Today we talk about:

  • The 10 features of ageing
  • How we measure ageing
  • Senescence, Autophagy, Fasting, Mitochondria, DNA damage
  • Anti-ageing drugs and why senolytics are so exciting
  • Metformin
  • The supplements people are currently using for ageing
  • Gene and Stem cell therapy

Do check out  Andrew’s book, Ageless, and thedoctorskitchen.com for links to his YouTube channel and further work in the field of ageing.

 

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Summary

Thanks to Dr Andrew Steele for joining me on the show today – another superb guest – and a topic that I know a lot of you have been asking to hear more about again.  I hope you enjoyed our conversation and found it as interesting as I did.

 

Do check out the links to follow Dr Andrew on social media and his website.

 

Studies mentioned on the podcast
TAME Trial – https://www.afar.org/tame-trial


Guest: Dr Andrew Steele

Andrew Steele is a scientist, writer and campaigner based in London, and author of Ageless: The new science of getting older without getting old. After a PhD in physics from the University of Oxford, he decided that ageing was the single most important scientific challenge of our time, and switched fields to computational biology. He worked at the Francis Crick Institute, using machine learning to decode our DNA and predict heart attacks using patients’ NHS medical records.

He’s now a full-time science writer and presenter. He’s written for the Guardian, Telegraph and Wall Street Journal, am a regular expert on Impossible Engineering, and have featured on other shows on Discovery and the BBC. He also produces videos on his YouTube channel and gives live talks ranging from lectures in schools to science stand-up at the Hammersmith Apollo. He’s also campaigned about science funding as Chair of Science is Vital and creator of Scienceogram.


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